The Society of Nuclear Medicine and Molecular Imaging (SNMMI) strongly supports the Choosing Wisely® campaign. The SNMMI is an international scientific and medical organization dedicated to raising public awareness of nuclear medicine and molecular imaging and how they can help provide patients with the best health care possible. Nuclear medicine and molecular imaging can eliminate the need for exploratory surgery, providing a painless and safe alternative for diagnosing and treating patients. They can help physicians to diagnose, stage and assess the effectiveness of a treatment, allowing highly targeted, personalized treatments to be directed precisely at problem areas and helping patients receive the most effective and most cost-effective treatment sooner. The SNMMI believes that the right test should be performed and interpreted for the right patients by appropriately trained personnel on equipment that is operating safely. Thus, the guiding principles of the SNMMI are in close agreement with those of the Choosing Wisely campaign.