American Academy of Pediatrics – Section on Cardiology and Cardiac Surgery

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Released November 2, 2020

Do not order troponins for the routine evaluation of pediatric chest pain in the absence of a concerning history or electrocardiogram (ECG) abnormalities.

Troponin-I levels are a valuable tool for the assessment of adult patients who present with chest pain. However, these levels are not as useful in the pediatric population. Troponin levels in the great majority of pediatric patients presenting with chest pain are normal. Furthermore, troponin levels have not been shown to reliably correlate with disease severity or prognosis in many cardiac diseases known to cause chest pain in pediatric patients. However, in a few circumstances, such as a family history of very early cardiovascular disease or a history suggestive of myocarditis/pericarditis, consideration of troponin levels is reasonable. Therefore, do not order troponin levels for the routine evaluation of pediatric chest pain in the absence of a concerning history or ECG abnormalities.

These items are provided solely for informational purposes and are not intended as a substitute for consultation with a medical professional. Patients with any specific questions about the items
on this list or their individual situation should consult their physician.

How The List Was Created

This list was developed initially by faculty in Pediatric Cardiology at University Hospitals in Cleveland OH. It was then revised and approved by the AAP Section on Cardiology and Cardiac Surgery. After review by other AAP sections, the AAP Executive Committee granted final approval of the list.

AAP’s disclosure and conflict of interest policy can be found at


Brown JL, Hirsh DA, Mahle WT. Use of troponin as a screen for chest pain in the pediatric emergency department. Pediatr Cardiol. 2012;33(2):337-342

Liesemer K, Casper TC, Korgenski K, Shaji SC. Use and misuse of serum troponin assays in pediatric practice. Am J Cardiol. 2012;110(2): 284-289