American College of Occupational and Environmental Medicine

View all recommendations from this society

Released February 24, 2014; Revised October 25, 2019

Don’t recommend the use of marijuana, cannabis, cannabinoids, and/or cannabidiol for treating workers with depressive disorders.

At this time there is no quality evidence for the use of cannabinoids for treatment of depressive disorders. Cannabinoids have significant adverse effects, and in the absence of evidence they are not recommended.

These items are provided solely for informational purposes and are not intended as a substitute for consultation with a medical professional. Patients with any specific questions about the items on this list or their individual situation should consult their physician.

How The List Was Created

The American College of Occupational and Environmental Medicine (ACOEM) routinely develops evidence-based clinical practice guidelines to assist physicians in improving or restoring the health of those workers who incur occupationally related illnesses or injuries. ACOEM’s Practice Guidelines, developed by expert panels, are the gold standard in effective treatment of occupational injuries and illnesses and are the only evidence-based guidelines that focus on returning employees to work within 90 days of an injury or illness. In addition, the College promotes the high-quality practice of occupational and environmental medicine (OEM) through the publication, via the scientific peer-reviewed Journal of Occupational and Environmental Medicine, of position statements and guidance documents relevant to the field. These documents are developed by ACOEM task forces made up of physician member volunteers and are approved by the Board of Directors.

After input from ACOEM leaders and approval from the Board of Directors, five topics were selected from the Practice Guidelines and the ACOEM position paper on fatigue risk management in the workplace for this campaign. The position paper and the methodology for the development of the Practice Guidelines are available at

ACOEM’s disclosure and conflict of interest policy can be found at


American College of Occupational and Environmental Medicine. ACOEM Practice Guidelines: Depressive Disorders. MDGuidelines website. [In Press September 2019.]